rsbP [2017-8-11 16:0:3]

protein serine phosphatase, energy PP2C, dephosphorylates RsbV

locus: BSU34110

pI: 4.83

mw: 45.87 kDa

protein length: 403 aa

gene length: 1209 bp

function: control of SigB activity

product: protein serine phosphatase, energy PP2C

essential: no

ec: 3.1.3.3

synonyms: yvfP

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]

Gene

Coordinates: 3,500,386 → 3,501,597

The protein

Catalyzed reaction/ biological activity

• dephosphorylation of [protein|AC64DA463250A090A62E50901EFE653C8F963872|RsbV] in response to red light, this results in [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB] activation [Pubmed|19948797]

[SW|Domains]

• N-terminal [SW|PAS domain], central coiled-coil domain, C-terminal PP2C phosphatase domain

Effectors of protein activity

• activity is stimulated upon interaction of the RsbP oligomer with RsbQ [Pubmed|21980452]

Expression and Regulation

Operons

• genes: [gene|9284E58A2D5394A31658E70879874A1338CF531B|rsbP]-[gene|53496D7AC05B20C5AEB6CB9B9B8825FC987B12C5|rsbQ]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A488 (yvfP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/488 NBRP B. subtilis, Japan]

Labs working on this gene/protein

• [SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]

References

Reviews

• 20658979

Original publications

• 27977677,19948797,21980452,10632888,15632289